Recent developments in technology allow fluorescence measurements to be carried out on individual molecules to monitor the stochastic fluctuations and changes in state underlying ensemble behavior. Protein folding or aggregation, and protein dynamics within cells can be followed at the molecular level, and localization of thousands of individual fluorescent molecules leads to images of molecular structures beyond the diffraction limit. BCM students have access to outstanding facilities for single molecule spectroscopy and super-resolution microscopy.
Profiles of Faculty Working on Single-Molecule and Super-Resolution Fluorescence
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